EBC - ON DEMAND
European Bifurcation Club 2008 – EBC 2008 – Prague, Czech Republic
LM stenting or surgery ?
ISAR-LEFT MAIN: A Randomized Clinical Trial on Drug-Eluting Stents for Unprotected Left Main Lesions
Author: Julinda Mehilli, MD, Deutsches Herzzentrum, Technische Universität Munich, Germany
OBJECTIVE
to assess the relative efficacy of the sirolimus- eluting stent (Cypher) and paclitaxel-eluting stent (Taxus) in patients with unprotected LMCA lesions.
SUMMARY
- This trial, the largest LM randomized trial to date, shows that unprotected LM stenting with Cypher or Taxus is feasible and safe at short-term.
- Cypher and Taxus stents provide comparable short- term safety.
- One-year outcomes (primary endpoint of the trial) will better clarify whether there are differences between these devices and will be presented at the TCT 2008