Nordic BBC meta analysis 1 vs 2 stents
European Bifurcation Club 2010, EBC 2010 – Budapest, Hungary
Simple or complex stenting for bifurcation coronary lesions: a patient-level pooled-analysis of the Nordic Bifurcation Study (NORDIC I) and the British Bifurcation Coronary Study (BBC ONE)
Author: Miles Behan, MD, Edinburgh Heart Centre, UK
- The treatment of bifurcation lesions remains a considerable challenge to interventional cardiologists
- Several trials have compared simple (provisional) vs complex (two-stent) strategies in DES
- We have combined the patient-level data of two of the largest randomised trials NORDIC I and BBC ONE
- Large dataset of bifurcation stenting allowing meaningful analysis and subgroup analysis
- This pooled analysis of the NORDIC I and BBC ONE Trials shows that the simple strategy is associated with lower rates of the composite endpoint of death, MI and TVR at 9 months.
- A simple strategy resulted in lower procedure duration, fluoroscopy times, contrast volume and reduced risk of periprocedural MI.
- Surgical TVR was significantly higher in the Complex group.
- No benefit of complex strategy in ‘true’ bifurcations, lesions with wide bifurcation angles, those with large SBs, long SB lesions and equivalent sized vessels.