EBC - ON DEMAND
European Bifurcation Club 2014 – EBC 2014 – Bordeaux, France
BVS (2): Time for clinical data
Pathological Aspects of Bioresorbable Stent Implantation
Author: Michael Joner CVPath Institute, Gaithersburg, MD
SUMMARY
- Thick Stent Struts in Current Generation BRS Result in Increased Acute Thrombogenicity and Delayed Endothelialization Compared to Contemporary Thin Stent Strut DES
- Chronic Inflammatory Reactions Need to be Carefully Characterized in BRS as This Will Impact on Clinical Performance
- Late Lumen Enlargement is a Phenomenon Observed in Preclinical and early Clinical Experience and may be an Differentiating Hallmark of BRS when Compared to DES
- Inflammatory Reactions in BRS have been Linked to Late Lumen Enlargement and this Association Deserves Further Investigation