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Pathological Aspects of BRS Implantation

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European Bifurcation Club 2015 – EBC 2015 – Athens, Greece

BRS in bifurcations (1)

Pathological Aspects of BRS Implantation

Author: Michael Joner, MD,CVPath Institute, Gaithersburg, USA

 

SUMMARY

  • Key issues identified in preclinical evaluation of BRS:
    • Acute Thrombogenicity
    • Endothelialization of stent struts
    • Acute radial strength and recoil
    • Inflammatory responses (acute and chronic)
    • Degradation kinetics and remodeling
  • Bifurcation Stenting using T-Stenting with Absorb results in substantial recirculation within the carina (neocarina) resulting in neointimal growth at the carina
  • Provisional Stenting with Absorb results in recircula6on at the lateral wall resulting in neoin6mal growth at the lateral wall

 

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