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Stenting on Endothelial Shear Stress


European Bifurcation Club 2015 – EBC 2015 – Athens, Greece

Novel insights from bench and simulation

Stenting on Endothelial Shear Stress

Author:  Ghassan S. Kassab, California Medical Innovations Institute, San Diego, CA



  • The simulations predict a negative hemodynamicrole for SB stenting which is exaggerated with a longer stent, consistent with clinical trial findings that dual stenting is comparable or inferior to provisional stenting.
  • Shorter SB stent (only to cover the stenosis) reduces negative effects on the SB by lowering the OSI as compared to provisional stenting, but increases the WSSG.
  • Undersized stents exaggerate the negative hemodynamic effects of SB stenting.


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