You are currently viewing From QFR to OFR: Intracoronary OCT derived FFR for Assessment of Stenosis Severity

From QFR to OFR: Intracoronary OCT derived FFR for Assessment of Stenosis Severity

EBC - ON DEMAND

European Bifurcation Club 2019, EBC 2019 – Barcelona, Spain

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From QFR to OFR: Intracoronary OCT-derived FFR for assessment of stenosis severity

Author: Shengxian Tu, MD, PhD, Shanghai Jiao Tong University, China

 

Limitations of angiography-based FFR

  • Angiographic image overlap and significant foreshortening
  • Post-PCI optimization: stent mal-apposition/under-expansion

OFR Analysis Steps

  1. Automatic OCT lumen contour delineation and 3D reconstruction
  2. Automatic reconstruction of cut- planes at the side branches ostia
  3. Compute OFR using the QFR algorithm

SUMMARY

  • OFR (OCT-based FFR) provides lesion morphology and physiological assessment in a single OCT pullback.
  • Compared with FFR, OFR showed good diagnostic accuracy, excellent reproducibility and short analysis time.
  • OFR had substantially better diagnostic accuracy than OCT-MLA.
  • OFR is promising for use in the cath lab for PCI optimization.

 

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