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Impact of side branches modeling on computation of endothelial shear stress in coronary artery disease

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Impact of side branches modeling on computation of endothelial shear stress in coronary artery disease

European Bifurcation Club 2015 – EBC 2015 – Athens, Greece

Novel insights from bench and simulation

Impact of side branches modeling on computation of endothelial shear stress in coronary artery disease

Author: Juan Luis Gutiérrez-Chico, MD, PhD, Charité Universitätsmedizin Berlin, DE

 

DISCUSSION/CONLUSION

  • Feasibility of QCA-OCT fusion
    • Accurate real 3D cartesian reconstruction
  • Feasibility of true anatomical tree models
    • Accurate hydrodynamic / biomechanical calc
  • Conventional single-conduit models
    • Overestimate outflow
    • Underestimate Pd/Pa
    • Inaccurate SS
  • Implications
    • Former evidence (inconsistencies)
  • Need to implement tree models in future studies
    • Shear stress
    • Coronary physiology

 

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