ISAR-LEFT MAIN: A Randomized Clinical Trial on Drug-Eluting Stents for Unprotected Left Main Lesions

ISAR-LEFT MAIN: A Randomized Clinical Trial on Drug-Eluting Stents for Unprotected Left Main Lesions

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European Bifurcation Club 2008 – EBC 2008 – Prague, Czech Republic

LM stenting or surgery ?

ISAR-LEFT MAIN: A Randomized Clinical Trial on Drug-Eluting Stents for Unprotected Left Main Lesions

Author: Julinda Mehilli, MD, Deutsches Herzzentrum, Technische Universität Munich, Germany

 

OBJECTIVE

to assess the relative efficacy of the sirolimus- eluting stent (Cypher) and paclitaxel-eluting stent (Taxus) in patients with unprotected LMCA lesions.

SUMMARY

  • This trial, the largest LM randomized trial to date, shows that unprotected LM stenting with Cypher or Taxus is feasible and safe at short-term.
  • Cypher and Taxus stents provide comparable short- term safety.
  • One-year outcomes (primary endpoint of the trial) will better clarify whether there are differences between these devices and will be presented at the TCT 2008

 

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