EBC - ON DEMAND
The role of OCT in optimization of bifurcation PCI
European Bifurcation Club 2012 – EBC 2012 – Castelldefels, Spain
OCT imaging session
The role of OCT in optimization of bifurcation PCI
Author: Dr. Andrejs Erglis Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, LATVIA
XIENCE OPTIMAL STUDY
- Pilot, prospective, consecutive, one centre registry analyzing feasibility of OCT-guided XIENCE-PRIME stent implantation for the treatment of bifurcation coronary artery disease.
- Study population: Elective patients with non-left main bifurcation coronary artery disease involving at least 2 segments of the bifurcation; Sample size 70
- Hypothesis:
- Treatment of bifurcation coronary disease with XIENCE PRIME is safe andfeasible with similar performance (non-inferior) to historical control
- Acute and long-term outcomes of OCT-guided bifurcation treatment with XIENCE PRIME will be better than angiography guided treatment in historical control
CONCLUSION
- Intravascular optical coherence tomography (OCT) enables highly detailed assessment of lumen and calcium after different plaque modification strategies
- In Xience Optimal study, after plaque modification with angiosculpt or cutting balloon OCT revealed dissections in all patients, there was trend to higher rate of calcium fractures after cutting balloon
- OCT may improve our understanding of lesion morphology and is hypothesis rising for novel treatment strategies