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Pathological Aspects of Bioresorbable Stent Implantation

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Pathological Aspects of Bioresorbable Stent Implantation

European Bifurcation Club 2014 – EBC 2014 – Bordeaux, France

BVS (2): Time for clinical data

Pathological Aspects of Bioresorbable Stent Implantation

Author: Michael Joner CVPath Institute, Gaithersburg, MD

 

SUMMARY

  • Thick Stent Struts in Current Generation BRS Result in Increased Acute Thrombogenicity and Delayed Endothelialization Compared to Contemporary Thin Stent Strut DES
  • Chronic Inflammatory Reactions Need to be Carefully Characterized in BRS as This Will Impact on Clinical Performance
  • Late Lumen Enlargement is a Phenomenon Observed in Preclinical and early Clinical Experience and may be an Differentiating Hallmark of BRS when Compared to DES
  • Inflammatory Reactions in BRS have been Linked to Late Lumen Enlargement and this Association Deserves Further Investigation

 

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