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GHOST update: BRS in bifurcations, techniques, acute and long-term outcome

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European Bifurcation Club 2015 – EBC 2015 – Athens, Greece

BRS in bifurcations (2)

GHOST update: BRS in bifurcations, techniques, acute and long-term outcome

Author: Azeem Latib, MD, EMO-GVM Centro Cuore Columbus and San Raffaele Scientific Institute, Milan, Italy

 

INTRODUCTION

  • Bioresorbable vascular scaffolds (BVS) have emerged as an alternative to conventional metallic DES for the treatment of coronary artery disease.
  • Currently, BVS use is expanding from simple to more complex lesions such as bifurcations, calcific lesions, diffuse disease, thrombus-containing lesions, ISR and CTO, despite technical challenges associated with their implantation.
  • Of note, clinical outcomes after treatment with BVS for complex coronary lesions have yet to be fully clarified.

CONCLUSION

  • GHOST-EU represents one of the largest real-world cohorts of bifurcations treated with BVS
  • Provisional approach was default strategy (86%)
  • Cross-over from provisional to double-stenting in 4%
  • Elective double stenting only in 14%
  • BVS in bifurcations is associated with acceptable rates of MACE, TVF & TLR
  • Stent thrombosis rate of 2.5% at 12-months is concerning and is most probably related to learning curve and suboptimal technique

 

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